Antigen test sensitivity

Symptomatic people who have negative results from SARS-CoV-2 antigen tests should consider getting confirmation with a PCR test, as should asymptomatic people who have a positive antigen test, according to MMWR. Researchers studied antigen and PCR samples from over 1100 people presenting for COVID-19 testing. Among symptomatic people, the Sofia antigen test had a sensitivity of 80%, a specificity of 99%, a positive predictive value (PPV) of 94%, and a negative predictive value (NPV) of 96%. Among those without symptoms, the test had a sensitivity of 41%, a specificity of 98%, a PPV of 33%, and an NPV of 99%.

MMWR article on antigen test sensitivity