Characterization and clinical course of 1000 patients with coronavirus disease 2019 in New York: retrospective case series

Of the first 1000 COVID-19 patients admitted to a New York City hospital, 34% developed acute kidney injury and 14% required dialysis, researchers report in The BMJ. Over 90% of the cohort had major comorbidities at baseline. Roughly a quarter of patients were admitted to the ICU, and about one fifth overall died. Patients’ first intubations occurred most commonly at 3–4 days and at 9 days after symptom onset — which, the researchers say, “could suggest a biphasic nature” of the disease course. The median length of invasive ventilation was 6 days in patients who died, 9 days in patients who were discharged, and 29 days in those who were still hospitalized at the end of follow-up.

https://www.bmj.com/content/369/bmj.m1996