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Abstract Coronaviruses (CoVs) traffic frequently between species resulting in novel disease outbreaks, most recently exemplified by the newly emerged SARS-CoV-2, the causative agent of COVID-19. Herein, we show that … Read More
Remdesivir, a nucleotide analogue prodrug that inhibits viral RNA polymerases, has shown in vitro activity against SARS-CoV-2. 53 patients hospitalized for severe Covid-19 were treated with compassionate-use remdesivir. Clinical … Read More
The American Heart Association, American College of Cardiology, and Heart Rhythm Society have issued recommendations on using hydroxychloroquine and azithromycin to treat COVID-19 in patients with preexisting cardiovascular disease. … Read More
https://www.nejm.org/doi/full/10.1056/NEJMc2007575?query=pfw&jwd=000000762462&jspc=CD In the New England Journal of Medicine, physicians note that antiphospholipid antibodies can occur in critically ill patients, and they “may rarely lead to thrombotic events that are difficult … Read More
In JAMA Otolaryngology—Head & Neck Surgery, researchers describe a woman in her 40s who presented with sudden loss of olfactory function, without dysgeusia. There was no nasal obstruction, rhinorrhea, or … Read More
Researchers in China investigated how susceptible certain domesticated animals are to SARS-CoV-2. Writing in Science, they conclude that “ferrets and cats are highly susceptible … dogs have low susceptibility, … Read More
In EClinicalMedicine, Chinese researchers report on 34 asymptomatic patients who had elective surgeries during the virus’s incubation period. Symptoms quickly emerged after surgery. Some 44% of patients required intensive … Read More
A study in MMWR confirms that U.S. children with COVID-19 have a milder course than adults. As of April 2, youths accounted for 1.7% of all confirmed U.S. cases, … Read More
A woman with COVID-19 delivered at 39 weeks’ gestation. The woman and the neonate were discharged home on hospital day 6. Care was taken to avoid infecting hospital staff, … Read More
